Recombinant Human PRAME (aa 1-509) Protein, His
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
Cat: CX3178A
| Species | Human |
|---|---|
| Source | E. coli |
| Tag | His |
| Conjugation | Unonjugated |
| Format | Liquid |
| Purity | ≥90% by SDS PAGE |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Purification | Affinity purification |
| Buffer | Supplied in PBS with 8M Urea, and 0.05% SDS. |
| Application | WB; ELISA; Immunogen |
| AA Sequence | aa 1-509 |
| Shipping | The product is shipped at 4 ℃. Upon receipt, store it immediately at the temperature listed below. |
|---|---|
| Storage | Store at ≦ -20℃. Avoid freeze / thaw cycles. |
| Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
| Keywords | PRAME |
|---|---|
| Background | This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. |
| Synonyms | PRAME; PRAME nuclear receptor transcriptional regulator; OIP - 4; P78395; PRAME_HUMAN; Melanoma antigen preferentially expressed in tumors; Preferentially expressed antigen of melanoma; Q8IXN8 |
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