Proteins

Native Proteins

The folding, glycosylation and epitope landscape of the protein as it exists in nature.

native proteinnative antigencalibratorIVD raw material

Some assays simply cannot be built on a recombinant surrogate. When an antibody must recognise a glycosylated epitope, when a calibrator has to behave like the analyte in patient samples, or when a structural study needs the mature, processed form of a protein, native material remains the reference.

We purify native proteins from characterised starting material using salt fractionation, affinity and size-exclusion chromatography. Each preparation is documented with source, purification route and purity data, and is delivered with a statement on preservatives and stabilisers so that it can be transferred straight into a regulated workflow.

Applications

Typical applications, representative examples and use notes for Native Proteins
ApplicationRepresentative examplesWhen it fits
Assay calibrationTumour markers, plasma proteins, hormonesCalibrators and controls for immunoassay platforms where the native isoform defines the expected recovery.
Immunogen preparationGlycoprotein immunogens, multi-pass membrane targetsRaising antibodies against epitopes that are lost when a protein is expressed recombinantly in a prokaryotic host.
IVD raw materialAntigen for sandwich assay, blocking reagentsKit manufacturing, where the raw material must pass incoming QC and remain stable across the shelf life of the kit.

Product highlights

  • Authentic post-translational modifications and glycan profiles.
  • Conformational epitopes preserved for antibody screening and validation.
  • Traceable source material with documented purification history.
  • Available as calibrator-grade or bulk raw material for IVD production.
  • Stabiliser and preservative options matched to your buffer system.

Specifications & QC

Source
Human, bovine, porcine, plant or microbial material
Purity
≥90% by SDS-PAGE, silver stain on request
Form
Frozen liquid in PBS or lyophilised
Documentation
Source statement, CoA, purity gel

Related products & services

Next step

Tell us the target, we will tell you what is feasible

Send the sequence, assay format and sensitivity you need. You will get a technical assessment — recommended platform, timeline and the risks worth knowing before you commit budget.