Mouse Anti-Human TNFRSF10B DR5 CD262 Monoclonal Antibody, clone BT477
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
Cat: CX4249M
| Species | Human |
|---|---|
| Source | Mouse |
| Tag | N/A |
| Conjugation | Unonjugated |
| Format | Liquid |
| Antibody Isotype | IgG |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Purification | Affinity purification |
| Buffer | Supplied in PBS. |
| Application | ELISA; IP; IF |
| Shipping | The product is shipped at 4 ℃. Upon receipt, store it immediately at the temperature listed below. |
|---|---|
| Storage | Store at ≦ -20℃. Avoid freeze / thaw cycles. |
| Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
| Keywords | CD262 |
|---|---|
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
| Synonyms | DR5; TNFRSF10B; TRAILR2; Q9QZM4 · TR10B; Tumor necrosis factor receptor superfamily member 10B; dr-5; tra2 |
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