Mouse Anti-Human Interleukin-17 receptor A Monoclonal Antibody, clone BT489
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
Cat: CX4261M
| Species | Human |
|---|---|
| Source | Mouse |
| Tag | N/A |
| Conjugation | Unonjugated |
| Format | Liquid |
| Antibody Isotype | IgG |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Purification | Affinity purification |
| Buffer | Supplied in PBS. |
| Application | ELISA; IP; IF |
| Shipping | The product is shipped at 4 ℃. Upon receipt, store it immediately at the temperature listed below. |
|---|---|
| Storage | Store at ≦ -20℃. Avoid freeze / thaw cycles. |
| Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
| Keywords | CD217 |
|---|---|
| Background | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Synonyms | IL17RA; HIL-17R; CDw217; Q96F46; IL17A ; IL17F; IL17C; Interleukin-17 receptor A |
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